DPCstruct | MC29998

Metacluster Properties and Pfam Annotations

Number of structural domains3522
Mean domain length (aa)228 ± 44 aa
Standard deviation of domain lengths43.71
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score81.17
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.45
Mean intra-cluster local Distance Difference Test score0.39
Mean intra-cluster sequence similarity (%)12.83
Pfam Score97.41
Assigned Pfam label(s) PF19872- CL0041- PF20985- CL0052- CL0186

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1S3Y6B9 3-177 QADICHAYQLLKKGGLKDENIVVFMYDDIANNEENPRRGVIINSPHGEDVYKGVPKDYTGDDVTVDNFFAVILGNKTALSGGSGKVV…
A0A2D6G0K8 255-494 QKPTKQPVRTDINFGNYHALVIGINRYHNLPRLRTAVADAEAIADVLKSKYGFSVSTLINPTRTQILDRLDNLRAKLNRTDNLLIYY…
A0A7R9PWD3 4-159 None
A0A7R9PZM4 233-479 None
A0A7R9Q1B1 104-371 None
A0A497J7N3 527-707 None
A0A2R7SFF2 2-196 None
A0A7S1XMI0 98-322 None
A0A7G6A7Q8 40-238 None
A0A3S0YXL3 26-268 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.