DPCstruct | MC29990

Metacluster Properties and Pfam Annotations

Number of structural domains65
Mean domain length (aa)375 ± 79 aa
Standard deviation of domain lengths79.42
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score82.93
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.52
Mean intra-cluster local Distance Difference Test score0.62
Mean intra-cluster sequence similarity (%)19.71
Pfam Score79.95
Assigned Pfam label(s) PF13700- CL0219

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0Q0CMV5 176-591 RIYRALIEPLNQQHRNKLDELLTVKAGSNSTWLTWLRQSPLKPNSRHMMEHIERLKIFQLVALPEGLDGSIHQNRLLKLAREGGQMT…
A0A647ARD6 54-334 ALAEPLADAHRRRLDDLLKRRDNGKTTWLAWLRQSPAKPNSRHMLEHIERLKAWQALDLPTGIERLVHQNRLLKIAREGGQMTPADL…
E2CIR4 155-561 None
A0A1H6F177 26-400 None
A0A833N4D3 2-288 None
A0A2N3YUI4 149-525 None
A0A840NT60 8-339 None
A0A1S6R7B7 3-325 None
A0A0E3B8H8 174-577 None
A0A7W1LY68 2-344 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.