DPCstruct | MC29984

Metacluster Properties and Pfam Annotations

Number of structural domains45
Mean domain length (aa)372 ± 71 aa
Standard deviation of domain lengths70.89
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score77.84
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.37
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)24.52
Pfam Score83.12
Assigned Pfam label(s) PF16454- CL0465- CL0541

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2T7NNL3 3-466 AASKSHVDKDSLPANGLKEAQQQPYHVCVDSAKLDQPWFWPAIPREEAEQQLDGRPDGSFQIRKSSVKGNFTLVVRKNGDNSCIRII…
A0A2B4SX19 2-400 SASLNDASWYHGRITRDQAIDILLHRGRQEGLFLVRNKAGGSEDNFVLSLWHGNQALHFQIQCRGGINYSIDDGPIFEGLDSLIEYY…
A0A1B0F9N3 607-1034 None
A0A6A1QF04 259-592 None
A0A6P9A5C6 471-786 None
A0A6V7VIE9 6-458 None
A0A3Q0DYA0 129-423 None
A0A556TY20 58-309 None
A0A6P8S8E2 327-665 None
A0A7M3RVZ2 2-396 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.