DPCstruct | MC29977

Metacluster Properties and Pfam Annotations

Number of structural domains73
Mean domain length (aa)192 ± 25 aa
Standard deviation of domain lengths24.91
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score88.23
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.67
Mean intra-cluster sequence similarity (%)26.91
Pfam Score97.62
Assigned Pfam label(s) PF11860- CL0244

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7X6WY82 3-110 GLSEYTRLSVARQICEPAAYESASWGAFQIMGFHWQMLGYKSVQEMVADASRSEGAQLGQFVRFILADDALHKALKARKWSAFARIY…
A0A2V3UPH4 644-825 LEEARAEQMSRRLRADILAADGPGGFLDGPHLPKILFEAHIFDRETGGRFRASHPNISSRTWNRKLYVGGQGEWLRLYQAMQLDRRA…
A0A7R6YQQ0 12-196 None
A0A537MJX2 143-340 None
A0A562EW20 2-184 None
A0A259MQS1 3-170 None
A0A0V0QT32 55-252 None
A0A5C6V3R4 19-243 None
A0A2T5H0T1 88-280 None
A0A7M3DQI9 14-141 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.