DPCstruct | MC2995

Metacluster Properties and Pfam Annotations

Number of structural domains47
Mean domain length (aa)145 ± 18 aa
Standard deviation of domain lengths18.34
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score83.95
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.65
Mean intra-cluster sequence similarity (%)26.37
Pfam Score100.00
Assigned Pfam label(s) CL0319

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A540X389 7-150 TGDESPPPRWEVFSRGGEVAVRGEGRTPEVAFEQVALALCTRVTDPSTVEVREEVDVVCDAVDREGLLMDWLRSVVQLMGSRRLRFR…
A0A2K6AJY3 14-158 AQEEEDVRDYNLTEEQKAIKAKYPPVNRKYEYLDHTADVQLHAWGDTLEEAFEQCAMAMFGYMTDTGTVEPLQTVEVETQGDDLQSL…
A0A419IBD9 21-172 None
A0A1I8IEI0 9-154 None
A0A2I2Y839 1-135 None
A0A4Y7N9D9 9-174 None
A0A7V3HK68 300-458 None
A0A4Y7M6H8 8-141 None
A0A0V1A7T0 288-445 None
A0A3A0GCE1 129-276 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.