DPCstruct | MC2994

Metacluster Properties and Pfam Annotations

Number of structural domains11
Mean domain length (aa)162 ± 10 aa
Standard deviation of domain lengths9.70
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score90.42
Mean fraction of residues predicted as intrinsically disordered0.18
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)27.60
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1F1FNP8 242-409 RDSGSHTALILAGMWGAKAGAVPDMQERIQNFVDEGYPSRHFADQDFLEKELWAYIRQNLFAHDRLFDFCNAHEIPGEFYSNYQIAF…
A0A834IBN4 1-162 MRDYFSHTELILAGMWGGTRGAIHHIETLITDYIQTGNYLAKRVMDQHFLRYCIYPIIKQSMLHHDSLFEIQGSQPFPEHPIRDNYE…
A0A371YSD4 57-214 None
A0A2K0XS04 65-236 None
A0A6G6J0B2 158-311 None
A0A6N6XCI2 1-141 None
J9KBB9 268-424 None
A0A315AS20 40-214 None
A0A376BTU2 243-414 None
A0A376BK32 315-483 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.