DPCstruct | MC29884

Metacluster Properties and Pfam Annotations

Number of structural domains2919
Mean domain length (aa)158 ± 27 aa
Standard deviation of domain lengths27.49
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score81.82
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)12.37
Pfam Score93.74
Assigned Pfam label(s) PF00057- CL0110- PF05461- CL0111- PF01915

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A067BW35 234-372 None
A0A067C0U2 248-371 None
A0A067C869 369-505 None
A0A316RZS5 97-292 None
A0A672PHD8 28-225 None
A9WL78 211-372 None
A0A834T0H3 17-218 None
A0A834T297 1-258 None
A0A0G4H8V2 282-438 None
A0A0G4HLP4 692-852 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.