DPCstruct | MC29884

Metacluster Properties and Pfam Annotations

Number of structural domains2919
Mean domain length (aa)158 ± 27 aa
Standard deviation of domain lengths27.49
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score81.82
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)12.37
Pfam Score93.74
Assigned Pfam label(s) PF00057- CL0110- PF05461- CL0111- PF01915

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H3EUM6 145-288 None
H3EYU5 15-159 None
K1QZQ1 832-1045 None
A0A2C9U1A9 58-201 None
A0A6P5A046 27-176 None
A0A6P5AEA3 18-203 None
A0A2G9GDN7 6-163 None
A0A425BZ60 565-737 None
H2XMX4 57-192 None
A0A1C4SKG2 5-130 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.