DPCstruct | MC29884

Metacluster Properties and Pfam Annotations

Number of structural domains2919
Mean domain length (aa)158 ± 27 aa
Standard deviation of domain lengths27.49
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score81.82
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)12.37
Pfam Score93.74
Assigned Pfam label(s) PF00057- CL0110- PF05461- CL0111- PF01915

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6J0Y9F5 136-276 None
A0A4Q6XKQ5 90-246 None
D5EIK8 18-149 None
A0A1B8AVH1 13-247 None
A0A643C762 419-594 None
A0A0C3CGY2 52-262 None
A0A1Q4Z158 274-406 None
A0A1Q5A6K2 367-500 None
A0A2T3ML13 335-461 None
A0A317SS57 9-143 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.