DPCstruct | MC29884

Metacluster Properties and Pfam Annotations

Number of structural domains2919
Mean domain length (aa)158 ± 27 aa
Standard deviation of domain lengths27.49
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score81.82
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.48
Mean intra-cluster sequence similarity (%)12.37
Pfam Score93.74
Assigned Pfam label(s) PF00057- CL0110- PF05461- CL0111- PF01915

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6S7LHE3 100-237 FRSRGKLLGYGRLQVQKSGYCLDVEGNQGRGNVLIYNCEHAADQYFKFYKNGELVNKKSGLCVDIKGNNGYGDISMHACKDLPDQMW…
A0A402D0N4 20-183 LAGMPACAQDPASEAQGVTYQLINVNSGKVADVAGSSVTAGAQVFQYTYHGTKNQQWKVLPVDGGYWEIANVNSAQALTVVDTPTAN…
A0A1Y6BJA6 123-255 None
A0A1Q9C7T4 34-234 None
A0A1Y6C1D9 383-581 None
A0A1Y6BZW0 19-179 None
A0A1Y6CVD1 152-305 None
G8S9Z4 76-239 None
A0A1Q9C146 541-690 None
A0A1Q9C564 1109-1276 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.