DPCstruct | MC29873

Metacluster Properties and Pfam Annotations

Number of structural domains50
Mean domain length (aa)242 ± 36 aa
Standard deviation of domain lengths35.91
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score79.55
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.74
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)31.85
Pfam Score98.39
Assigned Pfam label(s) CL0020- PF12842

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3L6D951 3-243 NNISISNMEAKAKEFNEVIIQEQYYPWFAQYMVMKRASIEPNFHDLYLKFFDKVNSKSLNKEILKATYENCKVLLRSDLIKSSSEER…
A0A2P2MSE6 176-384 NIGTLEAAAERRTPIETPASETQDKISFIINNISSANVEAKAKEIPEILKEQYYPWFARYMVMKRASIEPNFHDLYLKFLDKVNSKA…
A0A6V7PPE6 320-580 None
A0A3L6DB33 83-315 None
A0A3L6DNK2 95-399 None
A0A1D6P0G0 1-256 None
A0A1B7NZN4 287-571 None
A0A3L6D7R4 3-207 None
A0A452Y250 16-224 None
A0A4Z1IT97 796-1029 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.