DPCstruct | MC2986

Metacluster Properties and Pfam Annotations

Number of structural domains48
Mean domain length (aa)450 ± 79 aa
Standard deviation of domain lengths78.57
Length coefficient of variation0.17
Mean AlphaFold2 pLDDT confidence score74.37
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)20.69
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
T1EZW2 7-426 KSFKKGLYIVSLVHQKGKVLVTGEDVLPTIEIQCEQTPSSVALKSDFYWLSKVICNWSNVKPLKNIFERPSTITDSLHFRSCLLQSV…
A0A022W0E6 1-488 MAKRVQQLSLACAYFDSSGSVMVAPDGSIPTHKITNHYVERSFADDEFNRVHPAFLWAFRASRNWTHLKQFIRGMNYNIKSDESMKQ…
A0A420I2T1 2-438 None
A0A6P7EMG1 1-311 None
H0EQP6 26-480 None
T1F4T2 193-605 None
J9AYF5 5-388 None
T5ABX8 261-666 None
A0A7J7TJX1 74-613 None
A0A5B7EWR4 12-390 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.