DPCstruct | MC29853

Metacluster Properties and Pfam Annotations

Number of structural domains143
Mean domain length (aa)168 ± 28 aa
Standard deviation of domain lengths27.59
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score80.86
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)18.79
Pfam Score46.49
Assigned Pfam label(s) CL0023- PF03849- PF13625- PF18307

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2T5X6L2 275-427 PQLGSQVYVLDDLSIIAPGPLASDTARALDRVATSEAHGLAPRYRLTTIALHHAFAHGDTADSVIGLLESMSLVPLSATVRSFITDA…
M3HL95 1-168 MSKPLIVQSDRTMLLEVDNPEFEACQSIVSKFAELEKSPEYLHTYRISPLSLWNAASIKMTADEIVECLEKFSRYSVPKNIVNEIRE…
A0A0F7SUA4 641-815 None
A0A6V2GKL7 61-246 None
A0A6A5DES2 146-351 None
A0A6A5DW76 980-1152 None
A0A7W1A817 158-316 None
A0A7K0W0R9 26-207 None
A0A847A3H0 220-387 None
A0A523DNI3 433-600 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.