DPCstruct | MC2985

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)58 ± 2 aa
Standard deviation of domain lengths1.85
Length coefficient of variation0.03
Mean AlphaFold2 pLDDT confidence score73.77
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.76
Mean intra-cluster local Distance Difference Test score0.87
Mean intra-cluster sequence similarity (%)65.02
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
J3PCS3 249-308 MMQPRTRPVQKFAQAVSQCSAEAAVYGKCIVEDYNAVHKDKCKKEFLKLKDCYLTASKKP
A0A022VZ19 1-58 MTGKTRPIEKFAQAAAKCSAEATVYGKCILADYTAVSKDMCAKEFMKLKDCYLVRVCS
A0A6G1G767 1-56 None
A0A656KHR8 1-58 None
A0A2T4BQJ1 2-59 None
A0A3M9YEV3 1-58 None
A0A059J9C1 1-59 None
A0A5C6SJR9 1-55 None
A0A2J6TQK0 1-56 None
A0A0C2IXH4 1-59 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.