DPCstruct | MC29802

Metacluster Properties and Pfam Annotations

Number of structural domains672
Mean domain length (aa)143 ± 30 aa
Standard deviation of domain lengths30.43
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score71.03
Mean fraction of residues predicted as intrinsically disordered0.37
Mean length-normalized TM-Score0.26
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)23.52
Pfam Score98.98
Assigned Pfam label(s) CL0003- PF04553- PF15697- PF08588- CL0537

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0V0R7R1 330-435 LINFKNQPCKITTQHNHKHCPYYHNAKDRKRPGTFYSTDLCEYIEKNENCPFFINCPKSHNRVEQLYQPDKYKTKFCTFYPNKVSQC…
A0A813H677 16-138 LQLFKTDLCKFFLENRCENGDSCSYAHEGVEVREKPDLTRTSMCRMLVKNGVCNSRTCRFAHTESELRATHGFFKMKMCVFAQSGRC…
A0A6G1EMR6 9-130 None
A0A0D2MEJ6 1-115 None
U6KMM5 3-157 None
H2AMF3 1-133 None
A0A1Y1UDP3 173-310 None
A0A1Y1V344 12-169 None
A0A6P6C3U0 33-206 None
A0A835XWI9 411-538 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.