DPCstruct | MC29793

Metacluster Properties and Pfam Annotations

Number of structural domains141
Mean domain length (aa)221 ± 41 aa
Standard deviation of domain lengths41.13
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score81.37
Mean fraction of residues predicted as intrinsically disordered0.34
Mean length-normalized TM-Score0.50
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)18.45
Pfam Score91.47
Assigned Pfam label(s) PF00177- PF02104- PF20456

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A097EIX4 6-194 LIPTLVVVTAVAAMIALGLWQLLDRAPKKEAYLAQLAANPAKPPIAFPATPDDRLLFRRTTATCARPLGQRLAGAGAAGFRLIADCG…
A0A383VI32 8-250 LLFLPSAVAATMAAWQVQRMQWKQGVVDEATRNMEQQAVDLLQGTVPEFRRVAVQGTYDHSRTAFVGPRPLSYEPKDPAVKLGMRPM…
A0A7R8X4Y6 63-297 None
J6FBI8 40-241 None
A0A1D8NQR7 180-430 None
A0A2A6FSZ5 80-356 None
A0A433RZD0 21-244 None
F4PXC1 23-219 None
A0A1P8ASC1 1-252 None
A0A2Z6MEF8 38-236 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.