DPCstruct | MC2974

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)55 ± 3 aa
Standard deviation of domain lengths2.64
Length coefficient of variation0.05
Mean AlphaFold2 pLDDT confidence score82.52
Mean fraction of residues predicted as intrinsically disordered0.36
Mean length-normalized TM-Score0.88
Mean intra-cluster local Distance Difference Test score0.91
Mean intra-cluster sequence similarity (%)75.48
Pfam Score60.71
Assigned Pfam label(s) PF00623- PF04997

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3A0HSR2 72-128 EKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRFRQNLLGKRVDYSG
A0A6A4QAT7 1-53 MCQEKLVQEFLDTLLDNGICGQPMRDGHNMVYKSFSDLIEGKEGRFRETLLGK
A0A803MIM7 1-53 None
A0A699GPC9 190-246 None
A0A803M6L0 738-790 None
A0A4Y7ICD5 968-1019 None
A0A6A4PHM1 1-59 None
A0A3Q7EC61 1-53 None
A0A811R5L9 1-53 None
A0A3S4X8W8 116-172 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.