DPCstruct | MC29626

Metacluster Properties and Pfam Annotations

Number of structural domains2794
Mean domain length (aa)147 ± 27 aa
Standard deviation of domain lengths26.70
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score85.46
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.49
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)15.42
Pfam Score96.73
Assigned Pfam label(s) CL0221- PF19257- CL0062- CL0219- PF12535

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0Q5HY08 74-203 IEEPPFVLPAGKQAAAGAVVVEPDGRLWLVAPSNAFGGYTATFPKGRAMGASLRATAIRETWEESGLSIVLTGWLGDFSRTQTHTRF…
A0A1I5DVG0 23-179 SQAHAEGVRHRTAHIWVVRDNGDKTEVLLQKRALNKDSFPGRYDTSSAGHIQAGDEPLESAIRELSEELGIQADADDLNFAGTFPIQ…
A0A7S4P767 492-658 None
A0A6A0JMY5 79-208 None
A0A7Y2ITW8 2-146 None
A0A7Y3DJS5 92-258 None
A0A1G6QDA0 26-154 None
A0A7Y4ZKQ3 2-130 None
A0A7K0C2I6 2-119 None
A0A7R9KNG4 256-391 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.