DPCstruct | MC2953

Metacluster Properties and Pfam Annotations

Number of structural domains77
Mean domain length (aa)185 ± 29 aa
Standard deviation of domain lengths29.45
Length coefficient of variation0.16
Mean AlphaFold2 pLDDT confidence score90.26
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.84
Mean intra-cluster local Distance Difference Test score0.77
Mean intra-cluster sequence similarity (%)37.28
Pfam Score94.88
Assigned Pfam label(s) CL0137- CL0014- CL0329- CL0221

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6N7X2I7 2-193 RKAEVNRSTGETQVQLYLDLDGSGWSEIDTGIGFMDHMLVLLAKHAGFDLKVKCQGDVYVDDHHSVEDIGISLGLAFAKALGDKQGI…
A0A6H5L408 272-460 SEEKRDATGVRRAEISRKTNETAITVDISLDGTGKAEVDTGLGFLDHMLHAMAKHGHLDLKLTCKGDLHIDDHHTAEDCAIALGEAF…
A0A5N6PZH9 65-197 None
R1C3L4 147-413 None
A0A446MPZ1 19-179 None
A0A1E7FWI6 14-228 None
A0A7C7DPR3 510-715 None
A0A812ISN5 1-122 None
A0A7X7XEC6 4-187 None
A0A645C0K0 96-282 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.