DPCstruct | MC29524

Metacluster Properties and Pfam Annotations

Number of structural domains314
Mean domain length (aa)187 ± 36 aa
Standard deviation of domain lengths35.74
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score80.20
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.42
Mean intra-cluster local Distance Difference Test score0.51
Mean intra-cluster sequence similarity (%)20.55
Pfam Score99.57
Assigned Pfam label(s) CL0192- PF08883- PF11807

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
T5ACM6 23-217 TDWYSPVHNEARIDFIDVKVNGTLLDLDHSLFRAPPSPQVDAAWERISSLAPHVIRTDHVLRLGKDPAVTARWSADWGFGPDAHVAE…
A0A6A6I4G9 33-207 LLYLSILITLALGASVFVGFLIGKSSAAGASLIPVPLTTRQFVYDRSFSYPPNNITNGAWGTLFPRQGGFFSHEPTIPDRSTLSVFH…
A0A094JPQ8 679-901 None
A0A4U0XQG4 23-242 None
W9WIZ1 33-224 None
A0A317VNE2 5-137 None
E5R1A5 92-316 None
A0A1V8SGZ3 52-265 None
A0A1B7YC23 57-298 None
A0A0H2S4K0 14-241 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.