DPCstruct | MC29517

Metacluster Properties and Pfam Annotations

Number of structural domains100
Mean domain length (aa)171 ± 26 aa
Standard deviation of domain lengths25.59
Length coefficient of variation0.15
Mean AlphaFold2 pLDDT confidence score82.64
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.73
Mean intra-cluster local Distance Difference Test score0.70
Mean intra-cluster sequence similarity (%)24.76
Pfam Score81.72
Assigned Pfam label(s) PF18256- PF07743- CL0063- CL0521- PF01521

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A424NHV2 7-167 NFFELFQLEVGFEVDLERLRGQFQILQREVHPDRYADQDPRSQRLATQWSMRVNEAFAVLSKPLSRAIYLLGLANVELEQNPSLEPE…
A0A1W1C547 3-163 NYFSIFDLKTDFEIDKIKLEQQYKEQIAQFHPDKFANSTADEKSQALQNTSLINTAYNTLKSDLNRAIYLLELNNIYPFDEKDTQMD…
A0A6A5DM43 287-477 None
A0A2B4SHC8 52-239 None
A0A2G2QP79 17-180 None
A0A4Y7L096 578-763 None
W6TF23 8-140 None
A0A2G5UC51 43-163 None
A0A800LRM9 3-103 None
A0A1W0E7J3 11-155 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.