DPCstruct | MC29473

Metacluster Properties and Pfam Annotations

Number of structural domains8059
Mean domain length (aa)214 ± 54 aa
Standard deviation of domain lengths54.30
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score77.78
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.30
Mean intra-cluster local Distance Difference Test score0.42
Mean intra-cluster sequence similarity (%)12.65
Pfam Score47.51
Assigned Pfam label(s) PF02377- PF18701- PF00140- CL0003- PF12017

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Y2BTW4 23-209 None
A0A812JYY2 14-219 None
A0A2K8RI65 65-301 None
A0A7D9JA82 4-118 None
A0A831Y657 2-113 None
A0A4S4BQF1 16-242 None
A0A397HE18 629-831 None
A0A397H1B9 158-397 None
A0A397G5T0 32-321 None
A0A397G5P4 237-423 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.