DPCstruct | MC29473

Metacluster Properties and Pfam Annotations

Number of structural domains8059
Mean domain length (aa)214 ± 54 aa
Standard deviation of domain lengths54.30
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score77.78
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.30
Mean intra-cluster local Distance Difference Test score0.42
Mean intra-cluster sequence similarity (%)12.65
Pfam Score47.51
Assigned Pfam label(s) PF02377- PF18701- PF00140- CL0003- PF12017

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H3H997 165-311 None
H3H986 6-132 None
H3H5I7 198-435 None
H3H2X0 54-229 None
A0A848C270 33-238 None
A0A6J0XLY8 122-290 None
J4VU17 125-365 None
A0A8A3TUC6 1-187 None
A0A380VDM4 2-150 None
A0A4Q8CDZ0 27-257 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.