DPCstruct | MC29473

Metacluster Properties and Pfam Annotations

Number of structural domains8059
Mean domain length (aa)214 ± 54 aa
Standard deviation of domain lengths54.30
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score77.78
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.30
Mean intra-cluster local Distance Difference Test score0.42
Mean intra-cluster sequence similarity (%)12.65
Pfam Score47.51
Assigned Pfam label(s) PF02377- PF18701- PF00140- CL0003- PF12017

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Q9DQS4 479-819 None
A0A250XME1 382-564 None
A0A5J4WR84 43-258 None
A0A5J4WNQ4 195-383 None
A0A5J4WM37 99-270 None
A0A5J4WKR6 118-313 None
A0A5N6NPC1 723-943 None
A0A5J4WIK0 359-548 None
A0A5J4WHS1 212-568 None
A0A5J4WFY7 26-311 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.