DPCstruct | MC29473

Metacluster Properties and Pfam Annotations

Number of structural domains8059
Mean domain length (aa)214 ± 54 aa
Standard deviation of domain lengths54.30
Length coefficient of variation0.25
Mean AlphaFold2 pLDDT confidence score77.78
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.30
Mean intra-cluster local Distance Difference Test score0.42
Mean intra-cluster sequence similarity (%)12.65
Pfam Score47.51
Assigned Pfam label(s) PF02377- PF18701- PF00140- CL0003- PF12017

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A381JB68 2-137 FGINLSQGTMINFNDYCHENLKSVEENIKNSIINSQGAIHFDETGISIDKKRQWLHVASNNKYTYYEAHQERGKEAVDAINILSNFN…
E7H5G0 34-248 NFTSPRQIPEDLREQIVDRFCKADVRDLSLTQAFYKLLDENKEYWCSLSTLYRLFRARGLNARRAPTREARRRSKPTAYSAEKPNEV…
A0A1Q9C203 242-442 None
A0A6P8CKF4 20-150 None
A0A081I5X0 14-220 None
A0A7M5VBQ6 88-316 None
A0A0D2P6W4 305-531 None
A0A1Q9BQK3 4-221 None
A0A1Q9C0Z7 513-707 None
A0A1Q9BYI7 371-564 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.