DPCstruct | MC29469

Metacluster Properties and Pfam Annotations

Number of structural domains8
Mean domain length (aa)114 ± 9 aa
Standard deviation of domain lengths9.43
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score79.48
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)36.20
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
H3BYX4 42-143 EKVKKLDCRKFLTPGYTTSGHVELHTVSVERGMSWEEATHIWADQNGPDDGFYVQKQMRNNKKTAILVKEVNTSKRLFLVYRPNTGR…
A0A7R8WF20 245-356 DKVTRVEKNVYESRHATGKAVTELHKVRVERGMSWQEAQEKYSTLLDDDEGFYVLKDGRNRMNRACAVLAVLRDPASLGKKKSPNAA…
A0A2I0TNK6 472-596 None
A0A7R9KDN0 184-307 None
A0A5K4F5D8 1173-1284 None
A0A402E7F9 326-424 None
A0A811X2H1 600-709 None
A0A6J1PZ46 350-473 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.