DPCstruct | MC2946

Metacluster Properties and Pfam Annotations

Number of structural domains29
Mean domain length (aa)74 ± 8 aa
Standard deviation of domain lengths7.77
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score90.70
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.82
Mean intra-cluster local Distance Difference Test score0.81
Mean intra-cluster sequence similarity (%)40.60
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7W9LGN3 124-195 GVVAYDVTEPRRPALVDYLSTRDFAGSVEDGTAGDVGPEGVFFVSAGDSPTRRPLLIVGNEVSGTTAIYEIR
A0A6H5KAZ9 1-74 MYAFVSLERIGGWMCWDASDATAPVFQSYVNSYEEDTAPESGAILPAEYSPTENALLLGAFEESNTLAIFELVV
A0A6N3UFN0 237-314 None
A0A1H9NS77 1-63 None
A0A1I1R078 14-83 None
W4QD95 323-394 None
A0A379Z634 95-177 None
A0A2S9XBI9 405-488 None
A0A376CJC4 277-358 None
A0A1W1UYS0 233-311 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.