DPCstruct | MC2945

Metacluster Properties and Pfam Annotations

Number of structural domains72
Mean domain length (aa)203 ± 41 aa
Standard deviation of domain lengths41.14
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score86.81
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.71
Mean intra-cluster local Distance Difference Test score0.64
Mean intra-cluster sequence similarity (%)29.71
Pfam Score100.00
Assigned Pfam label(s) CL0052

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6H5K9Q0 3-252 MSAAKGTPEPGPAWLVEERDACGVGFIANPKPEHKVVELGLAALGCMEHRGACLADNVSGDGSGIMTSVPWALLEREYSDMGVETDS…
A0A7U9RWB6 2-167 SGELITDSMKPMHDRSNGLGGGFAGYGIYPEYKEFYAFHMFFDTRDTRKECEAFLKERFEIIQSERIPTRRIPAITDEPIIWRYFIA…
A0A2X2E8K5 1-187 None
A0A0G4KM02 15-263 None
C4KHJ1 1-222 None
A0A811EBX1 8-238 None
A0A0R3T9F8 2-213 None
A0A536S0N2 11-241 None
A0A5E4PR16 10-184 None
A0A840TD97 8-238 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.