DPCstruct | MC29423

Metacluster Properties and Pfam Annotations

Number of structural domains44
Mean domain length (aa)73 ± 8 aa
Standard deviation of domain lengths7.90
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score82.45
Mean fraction of residues predicted as intrinsically disordered0.26
Mean length-normalized TM-Score0.85
Mean intra-cluster local Distance Difference Test score0.85
Mean intra-cluster sequence similarity (%)49.66
Pfam Score100.00
Assigned Pfam label(s) CL0039

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1S3SWF8 87-155 EDMVDPWNVSTTNAKGVDYDKLIVRFGSSKIDQELVDRIERVSGQKAHRFLRRGIFFSHRDMHQVLDAY
A0A1X7URX2 4-70 ESAQPKEQIVDPWTAKAGEGEKKINYDKLIVQFGSERIDESLLQRIETLSKKPAHHFLRRGIFFSHR
A0A4U5MNN9 46-126 None
A0A812U2E6 272-348 None
U6M0I2 214-278 None
A0A182EJZ3 2-70 None
A0A7D9DBL1 473-542 None
A0A5E4AQD0 172-244 None
A0A7R8H9F2 13-86 None
A0A2H2IAK5 16-90 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.