DPCstruct | MC29396

Metacluster Properties and Pfam Annotations

Number of structural domains45
Mean domain length (aa)181 ± 34 aa
Standard deviation of domain lengths34.35
Length coefficient of variation0.19
Mean AlphaFold2 pLDDT confidence score83.58
Mean fraction of residues predicted as intrinsically disordered0.22
Mean length-normalized TM-Score0.67
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)28.04
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2V8NSS7 2-187 EPFRTFSFRTEKGKPFVASARRKCRFLYFYFINRDFGLMPVKLQTRFPMPIQVYVNGHEWLARKLKQHAIRYTKRENAFLWIEDLAR…
A0A4R6EVE1 107-325 HVISAMEACPSYKPWHDKSSGKTYLRPETGKCLHYYFYFIDDELGLCYLRVPTWAPFGLQFYCNGHGAVARALKREGIGFVQADNAF…
F4LXC3 378-536 None
A0A7Y5SGM3 2-175 None
A0A2G6MTA3 9-167 None
A0A521UD49 1-146 None
I0WZH2 130-361 None
A0A498QK12 7-180 None
A0A081HXW5 113-336 None
A0A521V0Z7 18-166 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.