DPCstruct | MC29282

Metacluster Properties and Pfam Annotations

Number of structural domains24
Mean domain length (aa)270 ± 57 aa
Standard deviation of domain lengths56.50
Length coefficient of variation0.21
Mean AlphaFold2 pLDDT confidence score78.48
Mean fraction of residues predicted as intrinsically disordered0.16
Mean length-normalized TM-Score0.40
Mean intra-cluster local Distance Difference Test score0.58
Mean intra-cluster sequence similarity (%)21.76
Pfam Score77.22
Assigned Pfam label(s) CL0166- CL0245

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A0H3GPC0 343-594 VKALIIAHGYSTASSIAGVANRLIGEKIYQAMDMPMEVAFNDVSRAVVDYLQHTDTRAGVMVLIDMGYTKEIADALLSVINGPLVVV…
A0A1L8WQ84 8-264 IKSIVLAHGYSTASSMANVANRLLNKNVFQAYDMPLDITLEKIKAQLIRFIGEYRADSGLILLVDMGSLNQLGNMLIDHLNGPLLLF…
A0A7V6MV83 37-289 None
A0A2S3U8L8 4-330 None
A0A1S8TCJ1 1-204 None
A0A2L1TY20 240-651 None
A0A2X2T364 1-200 None
A0A6X9J5M3 538-858 None
A0A1B6ZB57 3-270 None
A0A2I8QIT8 510-858 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.