DPCstruct | MC29267

Metacluster Properties and Pfam Annotations

Number of structural domains67
Mean domain length (aa)226 ± 53 aa
Standard deviation of domain lengths53.35
Length coefficient of variation0.24
Mean AlphaFold2 pLDDT confidence score84.81
Mean fraction of residues predicted as intrinsically disordered0.23
Mean length-normalized TM-Score0.65
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)18.84
Pfam Score93.55
Assigned Pfam label(s) PF10067- PF20337

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A4Z0SHU0 22-233 FTCLLMAQTCFVIYLTLGYGLTGATSGMSDWNRLNSTAYVANDETGNFMYAAHVLLAIVMIIGGSLQLIPAMRKKHPRFHRYNGRIF…
A0A1Y2CKS3 37-260 TQSHESSHDIPLVPILIKRSWTPFSVAMTILSTFFNVYILAMYLVRNPKDWFGIGAIFKKTVMGTVSMYVHFVGGFAVNFIGIMQLV…
C1E414 148-434 None
A0A1I3DAC0 23-252 None
A0A7T8ZBL7 2-144 None
A0A7H5ETG2 4-142 None
A0A1Y2HLZ0 46-269 None
A0A1Q9CHB7 652-847 None
A0A2R7SEF2 1-135 None
L2GDZ0 6-349 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.