DPCstruct | MC29236

Metacluster Properties and Pfam Annotations

Number of structural domains1652
Mean domain length (aa)327 ± 87 aa
Standard deviation of domain lengths87.43
Length coefficient of variation0.27
Mean AlphaFold2 pLDDT confidence score81.22
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.49
Mean intra-cluster sequence similarity (%)16.70
Pfam Score98.39
Assigned Pfam label(s) CL0020- CL0013- PF09746- CL0168- CL0093

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7J0G2N3 5-220 None
H0ESR1 11-236 None
A0A812IR12 603-946 None
A0A182G1A9 58-408 None
A0A812ND66 61-419 None
A0A0D3C1E3 5-283 None
A0A7Y6TWC4 575-984 None
A0A7J9EKW8 24-305 None
A0A7J9EF39 13-289 None
A0A6A5ZCG5 9-187 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.