DPCstruct | MC29236

Metacluster Properties and Pfam Annotations

Number of structural domains1652
Mean domain length (aa)327 ± 87 aa
Standard deviation of domain lengths87.43
Length coefficient of variation0.27
Mean AlphaFold2 pLDDT confidence score81.22
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.51
Mean intra-cluster local Distance Difference Test score0.49
Mean intra-cluster sequence similarity (%)16.70
Pfam Score98.39
Assigned Pfam label(s) CL0020- CL0013- PF09746- CL0168- CL0093

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A378UVL9 18-306 SPAAIKRWVPFVDEITRAALDEHIESGEIDFVEHLANVVPAVFTLAMMGIELKKWNVYSEPTHASVYTPEHSPDREKINEQHREMGI…
A0A803NCQ6 31-343 NRPRLIGAKILGYDYTTILWAPYGPLWRNHRRIAATEILSPHRLHLLADIRSEEVRSLVKRINDHAAEGRDKTIEIKPALLELTNNI…
A0A0D2PQ57 18-275 None
A0A2D0QJ02 22-302 None
A0A022RDF2 3-180 None
A0A7N2LBD8 20-282 None
A0A7N2KTX3 86-452 None
A0A068UX80 165-601 None
A0A068UNM1 3-292 None
A0A2G8L2P9 142-428 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.