DPCstruct | MC2922

Metacluster Properties and Pfam Annotations

Number of structural domains116
Mean domain length (aa)172 ± 35 aa
Standard deviation of domain lengths35.13
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score82.98
Mean fraction of residues predicted as intrinsically disordered0.30
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.72
Mean intra-cluster sequence similarity (%)22.82
Pfam Score50.69
Assigned Pfam label(s) PF00499- PF20501- PF03334- PF13244

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A1Q9V8U2 219-379 DWVLVALVVVGTLGAVLARTRIAAIVVLGVVGFTMTLWYFALGAADVAITQLLVEILTVCVMVLLLRRLPLRFQREKKRPRIVAAVV…
A0A3M1J2R5 6-170 IFFALAAVAVLSALGVVFNKNVVHSALFLLLNFSTIAFLYFMLNAQFLGVAQILVYAGAIVVLFLFVVMLVGADVGEPLGNWLSGQN…
A0A7J0CZL1 14-186 None
A0A7C3DY83 17-189 None
A0A1R4FEJ2 27-205 None
A0A6L9J3N4 4-171 None
Q09EQ0 3-183 None
A0A7V4PAI2 63-267 None
A0A6A8G8J0 3-215 None
A0A445D565 149-302 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.