DPCstruct | MC29139

Metacluster Properties and Pfam Annotations

Number of structural domains532
Mean domain length (aa)242 ± 48 aa
Standard deviation of domain lengths48.09
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score87.10
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.53
Mean intra-cluster local Distance Difference Test score0.52
Mean intra-cluster sequence similarity (%)17.03
Pfam Score79.19
Assigned Pfam label(s) CL0258- PF19302- PF03485- CL0257- CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A7C1Q4C8 23-261 LLTGKVIFKDVWINYHIVDEKGHKMSKSLGNVIDPKDILDRFGAEPFRMWAAIEGNLVKTDFRCSFDRIDGAKKTITKLWNVARFIS…
A0A6D0J4Q7 1-178 IKASTWLNHFDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVNLASRNAGLIAKRFDGVLSAELADPELYKTFTDAAAA…
A0A7S3ZYJ7 11-334 None
A0A1A9VK50 659-880 None
A0A832B6G9 1-122 None
A0A2J8ABT9 14-236 None
A0A850KKR7 11-255 None
A0A1B0C165 987-1251 None
A0A1B0C1R2 363-633 None
A0A6J7VLH3 3-162 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.