DPCstruct | MC29083

Metacluster Properties and Pfam Annotations

Number of structural domains1056
Mean domain length (aa)384 ± 86 aa
Standard deviation of domain lengths86.46
Length coefficient of variation0.23
Mean AlphaFold2 pLDDT confidence score80.25
Mean fraction of residues predicted as intrinsically disordered0.21
Mean length-normalized TM-Score0.40
Mean intra-cluster local Distance Difference Test score0.43
Mean intra-cluster sequence similarity (%)13.77
Pfam Score80.84
Assigned Pfam label(s) CL0023- CL0489- CL0020- CL0512- PF12017

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
L8YCQ6 317-793 HHFEWQPPLKNVSSSTDVGIIDGLSGLASSVDDYPVDTIAKRFRYDCALVSALMDMEEAILEGLRALGLADYLGGPFTVVVKESCDG…
A0A815Z2U6 107-533 PPVYFFTFDLASQLQQILDCSTDLCLVNHAKNRPTTLQDIVDGEFYQRLLIAERGNNFLTLTMNVDGVSPNRSSSLSIWPVFLVINE…
A0A2H3BVA7 217-631 None
G0P3U4 103-660 None
A0A4S8MHQ7 346-838 None
A0A4S8MBS1 44-424 None
A0A818YWA1 560-1079 None
A0A5N6Q144 448-748 None
A0A2N9HZR0 121-489 None
A0A3N4JB11 2-250 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.