DPCstruct | MC29023

Metacluster Properties and Pfam Annotations

Number of structural domains188
Mean domain length (aa)111 ± 14 aa
Standard deviation of domain lengths13.81
Length coefficient of variation0.12
Mean AlphaFold2 pLDDT confidence score86.96
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.75
Mean intra-cluster local Distance Difference Test score0.74
Mean intra-cluster sequence similarity (%)31.50
Pfam Score99.21
Assigned Pfam label(s) CL0031- CL0266

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A6I9YG70 126-235 KEVFPENGWNVYDPILEYRRQGIPNESWRMTSLNEQYELCDTYPALLVVPANIPDEELKKVAAFRSRGRIPVLSWIHPESQATITRC…
A0A183EHR0 20-124 DGWNIFDTIREFNRMHVPNETWRITRINDRYDFADTYPAMLAVPATAIVEGEDFLQKVGEFRSKQRIPVLSWLHPITQASITRSSQP…
G4TAW5 357-459 None
A0A1R0GL63 125-236 None
A0A146KEF4 289-381 None
A0A4T0I2U1 445-555 None
A0A6J1WHH3 6-104 None
A0A2C9KAK0 187-300 None
A0A6I8PLV7 114-224 None
A0A835JS02 222-317 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.