DPCstruct | MC29008

Metacluster Properties and Pfam Annotations

Number of structural domains31
Mean domain length (aa)123 ± 15 aa
Standard deviation of domain lengths15.46
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score87.87
Mean fraction of residues predicted as intrinsically disordered0.19
Mean length-normalized TM-Score0.88
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)44.72
Pfam Score100.00
Assigned Pfam label(s) CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A212C6F8 90-190 MSTFIRRYSRYLNEKAFSYRQMAFDFARVKKGADGVMRTMAPEKLLKSMPILQGQIDALLEFDVHPNELTNGVINAAFMLLFKDLIK…
A0A183E7E2 3-136 QHVRRYGKYISEKIYTYRLCAFDFCKVKRGREDGLLRTMNTDKVVAVYALENYIQNDGDLLLKTLPILQNQIDALLEFQVTSAELNN…
A0A1Y2BXT5 72-235 None
A0A7J6ZB52 340-471 None
A0A814Z396 109-224 None
A0A1I8IDX4 76-189 None
A0A1I8ILW7 104-220 None
U4U6D0 17-138 None
A0A6F9CA38 1-101 None
A0A1I8GR57 124-245 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.