DPCstruct | MC29006

Metacluster Properties and Pfam Annotations

Number of structural domains37
Mean domain length (aa)141 ± 16 aa
Standard deviation of domain lengths15.70
Length coefficient of variation0.11
Mean AlphaFold2 pLDDT confidence score86.52
Mean fraction of residues predicted as intrinsically disordered0.20
Mean length-normalized TM-Score0.64
Mean intra-cluster local Distance Difference Test score0.71
Mean intra-cluster sequence similarity (%)29.68
Pfam Score100.00
Assigned Pfam label(s) PF10343

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2G5U2E9 128-266 LGPSESGKFIVQHGNLVKINESGVTKVAEQILEAAKDGSIKEALFLSPELHPKSGDKEAVQWVFLVDTINFSFWPDEGAHYDVSWNG…
A0A183E4N8 7-138 RLSPRESAKYVVTNSSGQIKLSEEGVQKAARLMLDAIRSGAYSEHSYSAIDVHPQNADRSAVDWIFLVDTINFSFWSEKSHFQVTFQ…
A0A6I9Q2K1 2-132 None
A0A842Z9L0 21-137 None
A0A556U267 9-161 None
A0A101X542 1-147 None
A0A2G9YXD1 1-123 None
A0A654H9E8 10-161 None
N1QE72 37-169 None
A0A1U7LGH0 61-181 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.