DPCstruct | MC29

Metacluster Properties and Pfam Annotations

Number of structural domains21
Mean domain length (aa)109 ± 8 aa
Standard deviation of domain lengths8.15
Length coefficient of variation0.07
Mean AlphaFold2 pLDDT confidence score82.02
Mean fraction of residues predicted as intrinsically disordered0.25
Mean length-normalized TM-Score0.78
Mean intra-cluster local Distance Difference Test score0.69
Mean intra-cluster sequence similarity (%)21.91
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A2U8W6H2 1-98 MANLRSERTGLPFVVFISQKDGARHDVRVKVSASAKVRADEMGSYAARPCRHTDGRRLPPHEEKLLEAWIEKNIDVLTRYWDGEIEY…
A0A6B2H1U5 18-132 KEFLYEDSWHHNEFLYMDSFSQNETGIENLIVWTGPNPNGFRIKVSNIPNRISSNYFFVMTLPDYQVIGQINEEFITPIIINQIKKW…
A0A1T4M0R6 7-109 None
A0A066PGX6 114-219 None
A0A5M8P0P4 72-182 None
A0A1M5KXK6 33-155 None
A0A0F9A687 62-166 None
A0A539DC33 21-126 None
A0A4R0Y6T6 394-498 None
A0A255TW74 4-114 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.