DPCstruct | MC28999

Metacluster Properties and Pfam Annotations

Number of structural domains7
Mean domain length (aa)130 ± 8 aa
Standard deviation of domain lengths7.92
Length coefficient of variation0.06
Mean AlphaFold2 pLDDT confidence score89.68
Mean fraction of residues predicted as intrinsically disordered0.15
Mean length-normalized TM-Score0.87
Mean intra-cluster local Distance Difference Test score0.82
Mean intra-cluster sequence similarity (%)44.42
Pfam Score100.00
Assigned Pfam label(s) CL0020

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A183DZE5 1-146 MTSAIDLAELFMTVLEKSKTPASPELLDRFQELFDRLPALLEKDLDTGSGQDRRKQYISLALKWTMAVAEKRSHQRRGHPALHRRIA…
A0A7F8R3R5 30-152 NSAADLSMLVLESLEKAEVEVADELLENLAKLFSLMDPNSPERVAFVSRALKWSSGGSGKLGHPRLHQLLALTLWKEQNYCESRYHF…
T1JH00 770-891 None
A0A218UIF4 1-134 None
A0A5E4PNB8 136-266 None
U4U1F5 487-618 None
A0A2K6N1B5 92-214 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.