DPCstruct | MC28989

Metacluster Properties and Pfam Annotations

Number of structural domains15
Mean domain length (aa)106 ± 9 aa
Standard deviation of domain lengths8.77
Length coefficient of variation0.08
Mean AlphaFold2 pLDDT confidence score82.15
Mean fraction of residues predicted as intrinsically disordered0.33
Mean length-normalized TM-Score0.60
Mean intra-cluster local Distance Difference Test score0.83
Mean intra-cluster sequence similarity (%)35.50
Pfam Score100.00
Assigned Pfam label(s) PF05183

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A183DR59 1-128 MNIALKHSKAVDFPKTGIPPDPLTRTWTKDENEKVIPPERACRWPDFMCKNHEPSYVSPRLVGQLFRRVHLLVDVFNHVGAVEDASP…
A0A4V5ZXV0 136-252 SIARKHSLAVDFPKTGKPPEKLTQTPKNGMPPEQPDRFPDFMERSTSPAYVSSSLNGQLYRRAKEMDSVLSQITDRQQTAAILLDPE…
B7Q2B5 97-202 None
A0A6A6M138 159-257 None
A0A445MFI0 10-111 None
A0A0A9F2B6 58-150 None
A0A4Y2IZ74 1-115 None
A0A6P3Z5L6 44-150 None
A0A6S7FT68 69-167 None
A0A2K3KUA6 2-98 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.