DPCstruct | MC28982

Metacluster Properties and Pfam Annotations

Number of structural domains1799
Mean domain length (aa)139 ± 25 aa
Standard deviation of domain lengths24.53
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score86.51
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)12.47
Pfam Score95.85
Assigned Pfam label(s) PF04279- PF12119- PF08354- CL0314- PF02770

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3R7F4H6 568-726 None
A0A0C9W7U3 239-377 None
A0A2E1MYX0 40-171 None
J2WWD8 14-138 None
A0A2K3QG65 661-815 None
A0A849FYP7 228-378 None
Q7QAU2 165-292 None
A0A536N7C3 15-162 None
A0A1D1W094 31-187 None
A0A0L0FWG3 147-273 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.