DPCstruct | MC28982

Metacluster Properties and Pfam Annotations

Number of structural domains1799
Mean domain length (aa)139 ± 25 aa
Standard deviation of domain lengths24.53
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score86.51
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)12.47
Pfam Score95.85
Assigned Pfam label(s) PF04279- PF12119- PF08354- CL0314- PF02770

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
M5BQJ0 217-361 None
G4Z7N9 374-496 None
A0A455V301 14-120 None
A0A7H8QKA9 567-712 None
A0A6N2HGC3 15-158 None
A0A1Y2EHD1 74-241 None
A0A7I7QAR6 310-433 None
M8AIQ6 2-113 None
A0A0R1VTV7 5-142 None
A0A485HIL5 15-155 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.