DPCstruct | MC28982

Metacluster Properties and Pfam Annotations

Number of structural domains1799
Mean domain length (aa)139 ± 25 aa
Standard deviation of domain lengths24.53
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score86.51
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)12.47
Pfam Score95.85
Assigned Pfam label(s) PF04279- PF12119- PF08354- CL0314- PF02770

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
U1GC95 17-183 None
A0A074WNE3 364-532 None
A0A395NUB0 137-274 None
A0A6D0F620 159-306 None
K0T7P5 281-414 None
K0T6X5 288-453 None
A0A7M3QME6 151-265 None
C7IPB4 50-166 None
A0A4D4KS06 2-109 None
A0A4D4KRK4 99-267 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.