DPCstruct | MC28982

Metacluster Properties and Pfam Annotations

Number of structural domains1799
Mean domain length (aa)139 ± 25 aa
Standard deviation of domain lengths24.53
Length coefficient of variation0.18
Mean AlphaFold2 pLDDT confidence score86.51
Mean fraction of residues predicted as intrinsically disordered0.24
Mean length-normalized TM-Score0.48
Mean intra-cluster local Distance Difference Test score0.46
Mean intra-cluster sequence similarity (%)12.47
Pfam Score95.85
Assigned Pfam label(s) PF04279- PF12119- PF08354- CL0314- PF02770

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A447MVR5 8-76 WPIRVYYEDTDAGGVVYHASYVAFYERARTEMLRHHHFSQQVLLAERVAFVVRKMTLEYYAPARLDRYA
A0A3M1J630 22-155 PFQPPYRFVDDITFFDEDRLQAHYTFKETEFFYPGHFPQRAVTPGAILGEAASQAVLALGIYLMRHEAAAEERMIFLTSHELRFKRA…
A0A162MRK4 1012-1158 None
A0A4R4DTB7 295-441 None
A0A0D2PA65 40-171 None
A0A151HAI1 150-321 None
A0A6G0XWF1 1-121 None
A0A349MIC3 9-143 None
A0A820B7G4 1-130 None
M1FE61 6-130 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.