DPCstruct | MC28968

Metacluster Properties and Pfam Annotations

Number of structural domains68
Mean domain length (aa)166 ± 33 aa
Standard deviation of domain lengths33.01
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score86.57
Mean fraction of residues predicted as intrinsically disordered0.34
Mean length-normalized TM-Score0.81
Mean intra-cluster local Distance Difference Test score0.79
Mean intra-cluster sequence similarity (%)35.86
Pfam Score91.76
Assigned Pfam label(s) CL0286- CL0279

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
Q4P525 281-441 MRTPEQAGAYVRKLQQLVRRIGASDGNMQEGSLRCDVNVSVNRIGEPFGTRCEVKNLNSVRFMMNAISFESHRQVKLLQQNGRVEQE…
B3RXE0 188-339 VLRSINTCTGNFDEGAIRVDANVSINRSGDPFGTRTEIKNISGLRLLGKAIDNEIERQINHVESGGKIVHETRGYDEKLGLTLRMRD…
A0A670J519 244-373 None
J8TSK7 72-249 None
A0A837Q2U1 6-107 None
K2S685 2-162 None
A0A4Y7L8Y3 232-397 None
A0A0G0V2N4 158-322 None
A0A044V152 124-283 None
L9JJ92 242-399 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.