DPCstruct | MC2895

Metacluster Properties and Pfam Annotations

Number of structural domains42
Mean domain length (aa)153 ± 19 aa
Standard deviation of domain lengths19.47
Length coefficient of variation0.13
Mean AlphaFold2 pLDDT confidence score75.33
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.55
Mean intra-cluster local Distance Difference Test score0.60
Mean intra-cluster sequence similarity (%)21.04
Pfam Score100.00
Assigned Pfam label(s) PF14218

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A822L7G7 1-150 MKHRQPCQILAMLFLTGAATFSVPEPSKSAGKGLFFCGQLQGKWNTFVKRPKRNIAIIEWTSNDFAESGWDNRKRCITVSDRFNQYA…
A0A2L2MZL9 1-138 MKLASLTNVLVAGGIALSATATINQPSQAESRRGFYCDTLGNKPVTVYTNPRGVSEPWIRWTSNYFRDAGYNKLTRCQDVSHRLENY…
A0A845VWS4 59-214 None
A0A846DD35 72-238 None
A0A251WAG8 1-161 None
I4FMD9 1-109 None
A0A0P4UPK4 1-170 None
A0A1X9L8Z5 24-191 None
U5DJS2 3-166 None
A0A7C3ZHU1 562-680 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.