DPCstruct | MC28945

Metacluster Properties and Pfam Annotations

Number of structural domains23
Mean domain length (aa)660 ± 134 aa
Standard deviation of domain lengths133.68
Length coefficient of variation0.20
Mean AlphaFold2 pLDDT confidence score81.25
Mean fraction of residues predicted as intrinsically disordered0.27
Mean length-normalized TM-Score0.43
Mean intra-cluster local Distance Difference Test score0.61
Mean intra-cluster sequence similarity (%)24.14
Pfam Score0.00
Assigned Pfam label(s) UNKNOWN

Seed Sequences

Each DPCstruct metacluster stores at most two representative sequences: the cluster center and the member with the highest pLDDT confidence score. When both point to the same domain, only one entry is shown.

Protein ID Range Seed Sequence
A0A3Q9D6Q9 203-1084 AYARLGFNEQGLHVINGESMLTLDGKLYAVEKPLDSRYYRIKHPSRPDAFKPDVRHNGTGAWHTELEYPQQWDRSTLLERLGHTAQA…
A0A2S8HP80 567-1249 ADTISRFKIDQDLGAAGTPEQFNSRYAALQQSEHEWVRLFQQQYPTLPKGAIEQIFDRYGVDIRQAPDVTEFRQVFTRLDSKARQYQ…
A0A5E7C6P0 183-869 None
A0A7K4EBT9 316-1030 None
A0A2R7R5E0 23-586 None
A0A3M3NZ68 73-913 None
A0A3M5W4X2 6-402 None
A0A560RUK5 82-822 None
A0A1B5F8Z0 94-778 None
A0A6I6V6B0 1-455 None

3D Structure Viewer

A maximum of two representative PDB files is stored per metacluster: the cluster center or the highest-pLDDT member. You can switch from them when possible.

AlphaFold Confidence (pLDDT)
Very high (pLDDT > 90)
High (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
pLDDT is a per-residue measure of local confidence.